WebChitinase-3-like protein 1 (CHI3L1), also known as YKL-40, is a secreted glycoprotein that is approximately 40kDa in size that in humans is encoded by the CHI3L1 gene. The name YKL-40 is derived from the three N … WebFeb 19, 2024 · Systemic sclerosis (SSc) is an autoimmune disease with completely undefined etiology and treatment difficulties. The expression of both protein coding and non-coding RNAs is dysregulated during disease development. We aimed to examine a possible regulatory axis implemented in the control of chitinase-3 like protein 1 …
Chitinase-3-like 1 protein complexes modulate macrophage-mediated ...
WebFeb 14, 2024 · NM_001374626.1 → NP_001361555.1 chitinase-3-like protein 1 isoform 2 precursor. Status: VALIDATED. Source sequence(s) AC137104 Consensus CDS CCDS87878.1 Related ENSMUSP00000119205.2, ENSMUST00000156873.8 Conserved Domains (1) summary cd02872 Location: 22 → 378 WebObjective: To evaluate the classifier performance, clinical and biochemical correlations of cerebrospinal fluid (CSF) levels of the chitinase proteins Chitotriosidase-1 (CHIT1), Chitinase-3-like protein 1 (CHI3L1) and Chitinase-3-like protein 2 (CHI3L2) in amyotrophic lateral sclerosis (ALS). Methods: CSF levels of CHIT1, CHI3L1, CHI3L2, … fnct bath
Chitinase domain-containing protein 1 - Wikipedia
WebChitinase 3-like 1 (CHI3L1) is a secreted glycoprotein that mediates inflammation, macrophage polarization, apoptosis, and carcinogenesis. The expression of CHI3L1 is strongly increased by various inflammatory and immunological conditions, including rheumatoid arthritis, multiple sclerosis, Alzheimer's disease, and several cancers. WebThe CLPs BRP-39/YKL-40 (also termed chitinase 3-like 1) inhibit oxidant-induced lung injury, augments adaptive Th2 immunity, regulates apoptosis, stimulates alternative … WebChitinase-3-Like Protein 1. YKL-40, a 40 kDa plasma protein, is the best-known protein from the CLPs group. YKL-40 lacks chitinolytic activity due to the mutation of glutamic acid to leucine in the chitinase-3-like catalytic domain. 27 The expression of YKL-40 was found in different mammalian organs and tissues (ie, ... green thumb runcorn