Web结果 ①细胞实验:与阴性对照组比较,shRNA-Rac1组Rac1 mRNA及其蛋白表达明显降低(P均0.05);与阴性对照组比较,shRNA-Rac1组各时间点细胞增殖速度明显降低(P均0.05)。②动物实验:对照组癌细胞接种4~8天均可见瘤体形成,观察组接种35天仅2只成瘤,且瘤体 … WebDec 30, 2024 · Cofilin, a filamentous actin (F-actin) binding and severing protein that belongs to the ADF/cofilin family of proteins, plays important roles in various stages of cancer progression including cell polarization and polarized migration [ 31 – 34 ], escape from apoptosis, and release of metalloproteases [ 35 ], all of which are important in the …
Localization of cofilin mRNA to the leading edge of migrating cells ...
WebCofilin is one of the primary actin filament severing proteins and its activation is often an early event in cell migration.7,8 Cofilin is activated by dephosphorylation on serine 3, … sword over the nile
RNA interference of cofilin in Chinese hamster ovary cells …
WebAnti-Cofilin antibody [EPR6375] - Loading Control (ab124979) Research with confidence – consistent and reproducible results with every batch Long-term and scalable supply – powered by recombinant technology for fast production Success from the first experiment – confirmed specificity through extensive validation WebKnockdown of cofilin attenuates mitochondrial fission and mitophagy induced by staurosporine/etoposide/CCCP. a, b MDA-MB-231 cells stably expressing Non-Target … WebJan 11, 2024 · To further evaluate the functional role of cofilin in STS-, ETO- and CCCP-induced mitochondrial fission and mitophagy, two lentiviruses carrying shRNA (shCofilin-1 and shCofilin-2) were... sword ownership nsw