Cthrc1 kda

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August undefined, 2024

WebCTHRC1, a 28-kDa secreted ECM protein, could promote cell migration via limiting collagen matrix deposition [16]. ... (TAMs) is associated with tumor progression and poor prognosis in endometrial ... Web25.3 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. ... There are no reviews for CTHRC1 Recombinant Protein (NBP2-52008). By submitting a review you will ...

CTHRC1 Antibody (1G12) (H00115908-M05): Novus Biologicals

WebCTHRC1 is a secreted glycoprotein with 12 repeats of the Gly-X-Y motif (a.a. 58-93 based on the pro-form seqeunce) that is reported to increase cell motility and promote cell migration by limiting the deposition of collagen matrix. WebCTHRC1 (Collagen triple helix repeat-containing protein 1) is a 28-30 kDa, secreted glycoprotein that bears similarity to the C1q/TNF alpha -related family of proteins. It is expressed by disparate cell types, including renal epithelium, neurons, osteoblasts, and smooth muscle cells. flu shots for pregnant mothers

Anti-CTHRC1 antibody (ab264411) Abcam

WebAll lanes : Anti-CTHRC1 antibody (ab264410) at 1/1000 dilution Lane 1 : UACC-62 whole cell lysate Lane 2 : MALME-3M whole cell lysate Lane 3 : SR whole cell lysate Lane 4 : HeLa (human epithelial cell line from cervix adenocarcinoma) whole cell lysate Lysates/proteins at 50 µg per lane. Developed using the ECL technique. Predicted band … WebCTHRC1 gene deletion leads to fatty liver (steatosis) formation in mice while others exhibited inactivation of the CTHRC1 gene also results in low bone mass. Description. CTHRC1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 234 amino acids (31-243 a.a) and having a molecular mass of 25.3kDa. ... WebThe molecular weight of secreted CTHRC1 (30 kDa) appears to be larger than that of cellular CTHRC1 (26 kDa). CTHRC1 has four different isoforms with molecular weights of about 12.3 kDa to 27 kDa ... flu shots edmonds wa

Collagen Triple Helix Repeat Containing 1, a Novel

Recombinant Anti-CTHRC1 antibody [EPR22851-145] …

WebCTHRC1 protein expression summary. Single band larger than predicted size in kDa (+20%) but partly supported by experimental and/or bioinformatic data. WebThe recombinant human CTHRC1 consists of 224 amino acids and has a predicted molecular mass of 24.5 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh CTHRC1 is approximately … greengate east beer distributingWebApr 15, 2002 · Hepatocellular carcinoma (HCC) Malignant behaviors microRNA-155-5p (miR-155-5p) Collagen triple helix repeat containing 1 (CTHRC1) GSK-3β-involved Wnt/β-catenin signaling; ... Osteosarcoma microRNA-338-3p Activator of 90 kDa heat shock protein ATPase homolog 1 Tumor suppressor Translational repression; 82. greengate ellie white

"WebFeb 8, 2024 · Collagen triple helix repeat containing 1 (CTHRC1) is an extracellular matrix protein that regulates tumor invasion and modulates the tumor microenvironment. However, the association of CTHRC1 with the prognosis and tumor-infiltrating lymphocytes of KIRP and KIRC has not been reported. " - Cthrc1 kda

Cthrc1 kda

WebProteolytic processing may generate multiple CTHRC1 isoforms. There is the potential for an intracellular full-length 33 kDa, 245 aa form, plus extracellular isoforms that are 28 kDa (aa 33-245), 26 kDa (aa 49-245), 20 kDa (aa 98‑245) and 18 kDa and 16 kDa in size, the last two representing variants of the 20 kDa form with C-terminal processing. WebMay 19, 2014 · The gene that coded for collagen triple helix repeat containing 1 (CTHRC1), located at chromosome 8q22.3, was overexpressed in HCC compared with normal or liver cirrhosis tissues and identified as a new HCC-related gene. ... Fig. 1D shows that the 26-kDa CTHRC1 protein was expressed in membrane fractions of the HepG2 …

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WebCTHRC1 is expressed in calcified atherosclerotic plaque and chondrocyte-like cells, in the hypothalamus, pituitary gland and remodeling tissues. Aberrant expression of CTHRC1 is present in human solid cancers and likely to be associated with … WebImmunohistochemistry-Paraffin: CTHRC1 Antibody [NBP2-31797] - Staining of human pancreas shows low positivity in glandular cells as expected. Immunohistochemistry-Paraffin: CTHRC1 Antibody [NBP2-31797] - Staining of human placenta shows strong cytoplasmic positivity in trophoblastic cells.

WebOct 11, 2024 · Collagen triple helix repeat containing-1 (CTHRC1) is a 28-kDa secreted protein reported to be involved in vascular remodeling, bone formation and morphogenesis. This study aimed to investigate the role of CTHRC1 in promoting the metastasis of EOC and to elucidate the underlying molecular mechanisms. Web~Two bands of 25-30 kDa (SDS-PAGE) Purity: ≥90% (SDS-PAGE) Endotoxin Content: 0.01EU/μg purified protein (LAL test). Concentration: 0.1mg/ml after reconstitution. ... Collagen triple helix repeat containing-1 (CTHRC1) is a 30kDa glycosylated secretory protein containing a short collagen-like motif contributing to vascular remodeling by ...

WebOct 26, 2024 · The function of collagen triple helix repeat containing 1 (CTHRC1) as an oncogene has been reported in a growing number of publications. ... Highly conserved from lower chordates to mammals, the CTHRC1 protein was identified as a 30 kDa secreted protein and was first verified to be a differentially expressed gene in balloon-injured rat …

WebAll lanes : Anti-CTHRC1 antibody (ab264411) at 1/1000 dilution Lane 1 : UACC-62 whole cell lysate Lane 2 : MALME-62 whole cell lysate Lane 3 : SR whole cell lysate Lane 4 : NIH/3T3 (mouse embryo fibroblast cell line) whole cell lysate Lysates/proteins at 50 µg per lane. Developed using the ECL technique. Predicted band size: 26 kDa Exposure time: …

WebCTHRC1 (Collagen triple helix repeat-containing protein 1) is a 28-30 kDa, secreted glycoprotein that bears similarity to the C1q/TNF alpha -related family of proteins. It is expressed by disparate cell types, … flu shots hdWebFor the independent antibodies validation the evaluation is based on comparison of the staining of two (or more) independent antibodies directed towards independent epitopes on the protein. For all cases except the siRNA validation, an image representative of the antibody staining pattern is shown. flu shots for homebound patients nycWebMay 13, 2024 · CTHRC1 is highly expressed in patients with primary CRC and hepatic metastasis of CRC and predicts a poor prognosis. To … flu shot shoppers drug mart reginaWebCTHRC1 is overexpressed in multiple human cancers, and its expression is associated with increased migration and metastasis, as well as decreased survival (1-3). CTHRC1 expression is regulated through TGF-β/Smad3 … flu shot showerWebCthrc1 is a 30 kDa secreted protein that has the ability to inhibit collagen matrix synthesis. Cthrc1 is also glycosylated and retains a signal sequence … We recently identified collagen triple helix repeat containing-1 (Cthrc1) as a novel gene induced in adventitial fibroblasts after arterial injury. flu shot sign inWebCTHRC1 is specifically expressed in vascular calcifications of carotid artery lesions and may contribute to vascular remodeling of injured arteries (Pyagay et al., 2005 [PubMed 15618538]).[supplied by OMIM] green gate fairhope alabamaWebOct 6, 2024 · Collagen triple helix repeat containing 1 (CTHRC1), a 30 kDa protein is generally expressed in developing bones, cartilage, and myofibroblasts during wound healing 5. greengate fairhope alabama