Cytoplasmic sox10
WebMay 5, 2009 · Others have shown that Sox10 is a nucleocytoplasmic shuttling protein. We extend this observation and demonstrate that, in the cytoplasm, Sox10 is peripherally associated with the mitochondrial outer membrane. Both Sox10 and ARMCX3 are expressed in mouse brain and spinal cord as well as several cell lines. Overexpression … WebAbstract. SOX10 (Sry-related HMg-Box gene 10) is a key nuclear transcription factor in the differentiation of neural crest progenitor cells to melanocytes. It has been …
Cytoplasmic sox10
Did you know?
WebApr 5, 2013 · Nuclear staining of >10% tumor cells was considered positive for SOX10 and p63; cytoplasmic staining for Smooth muscle actin, calponin, CK14, CK5/6 and Glial fibrillary acidic protein; both ... WebSox10 shuttles between the nucleus and the cytoplasm. Since Sox10 can be found in the nucleus as well as in the cytoplasm, we addressed the question whether Sox10 has nucleocytoplasmic shuttling activity. An interspecies heterokaryon analysis was performed as originally described by Pinol-Roma and Dreyfuss .
WebJul 6, 2024 · In postnatal mice, melanocytes maintain and are maintained by expression of high levels of Sox10, while Sox10 activity in melanocyte stem cells is decreased 38. It is commonly accepted that ... WebApr 4, 2024 · Orthologous to human SOX10 (SRY-box transcription factor 10). [provided by Alliance of Genome Resources, Apr 2024] Sox10 SRY (sex determining region Y)-box 10 [ (house mouse)] Gene ID: 20665, updated on 4-Apr-2024. Summary. ... and nervous system development. Located in cytoplasm and nucleus. Is extrinsic component of …
WebIn ARM, cytoplasmic SOX10 was co-expressed with neuronal antigens in ~57% of submucosal and myenteric neurons, vs. ~3% in control. Furthermore, intrinsic gut neurons in ARM specimens co-expressed PLP1 (18%) and CDH19 (18%); however, neuronal co-expression of PLP1 and CDH19 was rarely (<2%) observed in controls. WebOct 1, 2012 · Sox10 is a marker of neural crest origin and is expressed in melanoma and peripheral nerve sheath tumors. •. This article explores Sox10 expression in various …
WebJan 10, 2024 · To isolate single Sox10 + /FSP1 − cells from Sox10 + /FSP1 + cells, we plated the mixed cell population at very low density (~100 cells per 100-mm dish), and …
natural herbs for anxiety depressionWebIn accord with its function as transcription factor, Sox10 contains two nuclear localization signals and is most frequently detected in the nucleus. In this study, we report that … maricopa association of governments youtubeWebSOX10 and/or S100 protein immunopositivity in conjunction with rearrangement of the PLAG1 gene assisted in reclassification of a subset of oncocytomas as oncocytic variants of PA and ME. Therefore, we recommend to include S100 protein and SOX10 IHC when diagnosing tumors with predominantly oncocytoma-like differentiation. maricopa animal shelter dogs for adoptionWebJan 4, 2024 · Confocal microscopy (Fig. 4e, f) demonstrated predominantly cytoplasmic localization in most of the SOX2x3Mut-transduced NSC, whether they had initiated differentiation (white arrowheads) or not... maricopa assembly of god maricopaWebSep 1, 2024 · Ten cases originally diagnosed as OC, and 1 low-grade uncertain oncocytic tumor (11/74) revealed nuclear-cytoplasmic and/or nuclear positivity for S100 protein and/or SOX10, respectively. Fusion transcripts CHCHD7-PLAG1 and GEM-PLAG1 were found in 2 cases (1 fusion in each), and these were confirmed by RT-PCR and PLAG1 … maricopa and pinal county boundariesWebJun 20, 2014 · Cytoplasmic staining for the pan-melanoma cocktail and nuclear staining for SOX10 and MITF were scored by 2 pathologists (J.C. and Y.G.). Positive staining in >1% … maricopa assessor\\u0027s office parcel searchWeb方法. 回顾性分析2016年2月至2024年1月上海市肺科医院与复旦大学附属肿瘤医院确诊的5例肺gct的临床资料、病理形态学特征及免疫表型特点，并复习相关文献。 maricopa associated government standards