WebRecently, DNA has been evaluated as a chiral scaffold for metal complexes to construct so called ‘DNA-based hybrid catalysts’, a robust and inexpensive alternative to enzymes. The unique chiral structure of DNA … WebMay 26, 2024 · Thus, the structure of biopolymers plays a crucial role in catalysis. The concept of DNA-based hybrid catalysts was first reported by Roelfes and Feringa in …
DNA-based hybrid catalysis. - Abstract - Europe PMC
WebMay 4, 2024 · DNA-based catalytic systems with improved efficiency, selectivity, and versatility remains an everlasting goal. We report here our effortstoward the development … WebArtificial Metalloenzymes and MetalloDNAzymes in Catalysis offers a comprehensive review of the most current strategies, developed over recent decades, for the design, synthesis, and optimization of these hybrid catalysts as … rosemere cancer foundation charity
Bioinspired Supramolecular Catalysts from Designed Self-Assembly of DNA ...
WebDec 4, 2024 · Biomolecular self-assembly, typically with de novo designed peptide or DNA as the building blocks, provides an effective avenue to orient and confine reactive groups into a catalytically active configuration to mimic and even rival the catalytic performance of native enzymes. In this Review, we discuss the chemical and structural properties of ... WebSep 3, 2008 · DNA in combination with the copper complex of 4,4'-dimethyl-2,2'-bipyridine (Cu-L1) gives rise to a rate acceleration of up to 2 orders of magnitude compared to Cu-L1 catalysis alone. Furthermore, both the enantioselectivity and the rate enhancement prove to be dependent on the DNA-sequence. WebJan 8, 2015 · A DNA hybrid catalysts comprises a transition metal complex that is covalently or supramolecularly bound to DNA. The chiral microenvironment and the second coordination sphere interactions provided by the DNA are key to achieve high enantioselectivities and, often, additional rate accelerations in catalysis. rosemere high school 1966