Lamp2蛋白作用

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August undefined, 2024

TīmeklisFurther, some of the functions of LAMP2 are believed to be protecting the lysosomal membrane from proteolytic enzymes that are within the lysosome itself (as in autodigestion), acting as a receptor into the lysosome for proteins, adhesion (when expressed on the outside surface of the plasma membrane) and signal transduction, … http://www.bioon.com.cn/doc/showarticle.asp?newsid=74708

リソソームによる細胞内分解を制御する分子装置のユニークな組 …

Tīmeklis2024. gada 1. janv. · LAMP2, an updated version of LAMP, holds 23 253 unique AMP sequences and expands to link 16 public AMP databases. In the current version, … Tīmeklis产品详细信息. PA1-655 detects lysosome-associated membrane protein-2 (LAMP2) from rat, mouse and human tissues. PA1-655 has been successfully used in Western blot, immunofluorescence, and immunohistochemistry. By Western blot, this antibody detects glycosylated and non-glycosylated LAMP-2, depending on the lysis buffer used. motorized lifter

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Tīmeklis2015. gada 10. dec. · The protein LAMP2 functions to protect lysosomal membranes from acid proteolysis. In this study, the authors show that malignant cells adapt to the acidic tumour microenvironment by redirecting ... Tīmeklis2024. gada 3. marts · 1、SQSTM1/p62蛋白. SQSTM1/p62 是一种多功能的蛋白，在大鼠、小鼠、人类和果蝇中分别称为ZIP，A170，SQSTM1和 Ref2cp。. … Tīmeklis2024. gada 8. febr. · LAMP2 gene encodes for three proteins, LAMP2A, LAMP2B, and LAMP2C, through an event of alternative splicing involving the exon 9 (in human) 5. The three isoforms share an identical luminal portion ... motorized lifting bed frames

Systemic AAV9.LAMP2B injection reverses metabolic and

Genetic LAMP2 deficiency accelerates the age-associated ... - PNAS

Tīmeklis根据自噬机制主要负责降解长寿命蛋白的特性，先让细胞在含有同位素标记氨基酸(比如14C-或3H-缬氨酸或亮氨酸)的培养基中生长一段时间(数小时至数天)，细胞在此期间 … Tīmeklis2024. gada 5. nov. · LAMP2在肿瘤细胞转移中发挥作用。可能在保护溶酶体膜免受自身消化，维持溶酶体酸性环境，表达于细胞表面（质膜）时有粘附作用的功能，以及细胞间和细胞内的信号转导。保护细胞免受甲基化诱变物的毒性作用。文章靶标对应Bioss抗体列表产品信息以官网为准。上一篇新品上市│用以制备免疫原的马来酰亚胺活化载 … motorized light fixture hoistTīmeklis2024. gada 28. marts · 总而言之，研究人员提出了LAMP2A在与ESCRT无关的过程中介导蛋白质包装到外泌体中，并且涉及HSC70对活性KFERQ序列的识别。 CD63 … motorized lighted cat toys

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Lamp2蛋白作用

Entry - *309060 - LYSOSOME-ASSOCIATED MEMBRANE PROTEIN 2; LAMP2 …

TīmeklisLysosome-associated membrane protein-2 (LAMP-2)はリソソームを形成する膜に豊富に存在する、高度に糖鎖付加されたタンパク質です。. 発見当初LAMP-2の役割は ... Tīmeklis2024. gada 24. nov. · Lamp2b-HuR融合蛋白功能化的外泌体能够将被RNA结合基序识别的RNA靶标驱动至溶酶体以在受体细胞中降解。该系统在富含溶酶体的巨噬细胞中 …

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TīmeklisRab7 和 Rab9 是小 Rab GTP 酶 Ras 超家族的成员 (1)。. 两种蛋白都位于晚期内体，但能发挥不同的功能。. Rab7 结合 RIPL效应蛋白可调控从早期内体到晚期内体再到溶 … Tīmeklis2024. gada 7. febr. · Lysosomal membrane permeabilization (LMP) has recently been recognized as an important cell death pathway in various cell types. However, studies regarding the correlation between LMP …

Tīmeklis2024. gada 25. aug. · LAMP2 would help researchers work on AMPs more efficiently and conveniently. Materials and Methods Data collection and compilation All the AMP sequences were collected from the scientific literatures or authoritative public AMP-related databases. In this updated LAMP2, the public AMP databases contain 16 … Tīmeklis溶酶体相关膜蛋白 1 和 2（LAMP1 和 LAMP2）是两种含量丰富的溶酶体膜蛋白 (1,2)。两者都是跨膜蛋白，并且在溶酶体的内腔面氨基末端被高度糖基化，这能保护蛋白质 …

Tīmeklis2024. gada 11. janv. · Introduction. Danon disease (DD) is a rare monogenic lysosomal storage disorder that was first reported in 1981 (Danon et al., 1981).It is caused by loss-of-function mutations in the LAMP2 gene that encodes for lysosome-associated membrane protein-2, lower levels of which will lead to disrupted autophagy … TīmeklisCells that lack LAMP2 express normal levels of VAMP8, but fail to accumulate STX17 on autophagosomes, which is the most likely explanation for the lack of fusion between autophagosomes and lysosomes (PubMed:27628032). Required for normal degradation of the contents of autophagosomes (PubMed:27628032).

TīmeklisLAMP2 has been suggested to play a role in protection of the lysosomal membrane from autodigestion, to maintain the acidic environment of the lysosome and to serve as an …

Tīmeklis2024. gada 8. dec. · Also known as Summary The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may play a role in tumor cell metastasis. It may also function in the protection, maintenance, and adhesion of the lysosome. motorized lightbandTīmeklis2024. gada 10. sept. · CD107a也被证明是淋巴细胞脱颗粒的标志物，如CD8+和NK细胞。. 细胞器标志物丨LAMP1抗体. Cat#：HPA014750. 规格：25ul/100ul. 应用类 … motorized light bulb changing systemTīmeklis2024. gada 5. nov. · LAMP2在肿瘤细胞转移中发挥作用。可能在保护溶酶体膜免受自身消化，维持溶酶体酸性环境，表达于细胞表面（质膜）时有粘附作用的功能，以及细 … motorized light filtering cellular shadesTīmeklis2016. gada 14. sept. · LAMP2 accumulated perinuclearly as well as at the edge and at the extensions of NE cells. Since LAMP2 is a membrane protein present in lysosomes, we used lysotracker, an acid-dependent dye, to determine co-localization of LAMP2 and these acidic subcellular compartments . Lysotracker staining quantification … motorized lightband separation systemTīmeklis2024. gada 25. aug. · LAMP2, an updated version of LAMP, holds 23 253 unique AMP sequences and expands to link 16 public AMP databases. In the current version, … motorized light filtering shadesTīmeklis2024. gada 7. nov. · Lamp2 knockout (KO) mice are characterized by disrupted autophagy and phagocytosis in hepatocytes, neurons, and leukocytes (23–26). Loss-of-function mutations of the human LAMP2 gene cause Danon disease, a lysosomal storage disorder characterized by cardiomyopathy, skeletal myopathy, and mental … motorized lighthouseTīmeklis2024. gada 27. jūl. · 在肿瘤转移过程中，LAMP1能作为microRNA抑制自噬并发挥抗肿瘤作用的直接靶点，其可通过引起溶酶体功能障碍并影响溶酶体水解酶的表达及活性发 … motorized lighthouse 21335