WebMay 20, 2024 · Targeting NRF2 phosphorylation regulation shows therapeutic potential for multiple inflammation-related diseases. Abstract The transcription factor nuclear factor erythroid-derived 2-like 2 (NRF2) participates in the activation of the antioxidant cytoprotective pathway and other important physiological processes to maintain cellular … WebMar 30, 2024 · The protein levels of phospho-Nrf2 and β-actin were determined. (F,G) ARE-luc plasmids transfected HPAEpiCs were pretreated (F) without or (G) with PP1, AG1478, LY294002, SH-5, APO, DPI, or NAC for 2 h and then incubated with vehicle or CORM-2 (30 μM) for 2 h. ARE promoter luciferase activity was determined in the cell lysates.
A major role for Nrf2 transcription factors in cell transformation by …
WebMay 4, 2024 · Expression of heme oxygenase-1 (HO-1), nuclear factor erythroid 2-related factor 2 (Nrf2), Bcl-2, Bax, Akt, and phospho-Ser473 Akt proteins in ischemic brain tissue was detected by western blot, while mRNA levels of Nrf2, HO-1, Bcl-2, and Bax were analyzed using real time quantitative PCR. In addition, HO-1 enzyme activity was measured ... WebDec 20, 2024 · Anti-Nrf2 (phospho S40, ARG40667, 225×) antibody was obtained from Arigo Biolaboratories. Anti-rabbit IgG conjugated with Alexa Fluro 488 (Invitrogen, Molecular Probe) was used as the secondary ... can my daughter get an irish passport
The KEAP1/NRF2 Signaling Pathway in Keratinization
WebApr 12, 2024 · Immunohistochemistry of phosphorylated Nrf2 (p-Nrf2) was performed in 110 patients with OSCC who underwent preoperative chemoradiotherapy and surgery. Nrf2 was stably upregulated in CRR cells... WebAnti-Nrf2 (phospho S40) antibody [EP1809Y] See all Nrf2 primary antibodies Description Rabbit monoclonal [EP1809Y] to Nrf2 (phospho S40) Host species Rabbit Tested … WebAug 11, 2024 · Cultures were stained with anti-p21, anti-phospho-NRF2 and anti-β-III-Tubulin, fixed with 4% PFA mounted in Fluoromount (Vector Labs, Burlingame, CA, USA). The immunofluorescence intensities of ... fixing crack in fiberglass tub