WebThe progressive ankylosis protein (ANK) is a transmembrane protein that transports intracellular pyrophosphate (PPi) to the extracellular milieu. In this study we show … WebSep 1, 2016 · Dominant or recessive mutations in the progressive ankylosis gene ANKH have been linked to familial chondrocalcinosis (CCAL2), craniometaphyseal dysplasia …
Regulation of fibroblast growth factor 23 (FGF23) in health …
WebAug 30, 2013 · It has been reported that subchondral bone explants from OA patients, secrete high levels of alkaline phosphatase (ALP), osteocalcin, osteopontin, IL-6, IL-8, and progressive ankylosis protein homolog (ANKH), urokinase plasminogen activator (uPA), prostaglandin and insulin growthfactor-1 (IGF-1) compared to normal bone explants . Webprogressive ankylosis protein homolog; Background. ANKH( AAH14526, 1 a.a. - 493 a.a.) recombinant protein with GST. Limitations. This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt. content marketing agency chattanooga
Management of temporomandibular joint diseases: a rare case …
WebThis family consists of several progressive ankylosis protein (ANK or ANKH) sequences. The ANK protein spans the outer cell membrane and shuttles inorganic pyrophosphate (PPi), a major inhibitor of physiologic and pathologic … WebRecently, the progressive ankylosis gene (ank) was shown to encode a multiple-pass transmembrane protein that regulates PP i transport from the cytoplasm to the … WebThis gene encodes a multipass transmembrane protein that is expressed in joints and other tissues and controls pyrophosphate levels in cultured cells. Progressive ankylosis-mediated control of pyrophosphate levels has been suggested as a possible mechanism regulating tissue calcification and susceptibility to arthritis in higher animals. effem poncitlan